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time enough for love-扮寂怎校低握(哂猟井)-及35嫗

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bad gene in its gonads´a happy oute。
  
  Both these statistical processes slowly weeded out bad genes from the race's gene pool。
  
  Unfortunately the first of these processes often produced babies viable but too handicapped�察�they needed help to stay alive´sometimes needing economic help�察�born losers�察�who never managed to support themselves�察�sometimes needing plastic surgery or endocrine therapy or other interventions or supports。 When Captain Aaron Sheffield had been practicing medicine ��on Ormuzd and under another name���察�he had gone through stages of increasing frustration over these poor unfortunates。
  
  At first he had tried to practice therapy by the Hippocratic Oath´or´close to it�察�he was by temperament unable to follow any man´made rule blindly。 Then he had had a period of temporary mental aberrance during which he had sought a political solution to what he saw as a great danger�此�reproduction by defectives。 He tried to persuade his colleagues to refuse therapy to hereditary defectives unless they were sterile or sterilized or´ willing to accept being sterilized as a precondition for receiving therapy。 Worse yet�察�he had attempted to include in the definition of ;hereditary defective; those who displayed no stigmata save that they had never managed to be self´supporting´´on a pla not overcrowded and which he himself had selected centuries earlier as nearly ideal for human beings。
  
  He got nowhere�察�he encountered nothing but fury and contempt´save for a few colleagues who agreed with him privately and denounced him publicly。 As for laymen�察�tar´andfeathers was the mildest medicine they prescribed for Dr。 ;Genocide。;
  
  When his license to practice was lifted�察 �Lazarus regained his normal emotional detachment。 He shut up�察�realizing that grim old Mother Nature�察�red of tooth and claw�察�invariably punished damnfools who tried to ignore Her or to repeal Her ordinances�察�he need not interfere。
  
  So he moved and changed his name again and started to get ready to go off´pla´when a plague hit Ormuzd。 He had shrugged and gone back to work�察�an unfrocked physician whose services were temporarily wele。 Two years and a quarter of a billion deaths later he was offered his license back´subject to good behavior。
  
  He told them what to do with that license and left Ormuzd as quickly as possible�察�eleven year later。 He was a professional gambler during that wait�察�that being the handiest way he could see at the time for saving up the necessary。
  
  Sorry�察�Minerva�察�I was talking about those mirror twins。 So the silly little wench was knocked up�察�which caused me to slip back into my baby´cotching�察�country´doctor persona�察�and I stayed up all night worrying about her and her brother and the baby they were going to have´unless I did something about it。 To find out what I should do�察�I had to reconstruct what had'happened and from that what could happen。 Having no certain data�察�I had to follow that old rule for finding a lost mule。
  
  First I had to think like that slave factor。 A man who auctions slaves is a scoundrel but too smart to risk a caper in which he might wind up a slave himself�察�or dead if he was lucky´which is what would happen to one who played fast and loose on Blessed with the authority of a bishop。 Ergo�察�the scoundrel had believed what he had said。
  
  That being so�察�I could table the question of why this factor was missioned to sell these two�察�while I tried to think like a priest´scientist engaged in human biological experimentation。 Forget the chance that these two were ordinary siblings´no point in picking such a pair even for a swindle。 Forget the chance that they were unrelated in any fashion�察�as in such a case it would simply be a normal case of breeding。 Sure�察�sure�察�any woman can give birth to a monster�察�as even with the most gei��ally hygienic of breeding a bad mutation can show up´and an alert midwife may neglect to give that first life giving spank´and many have。
  
  So I considered only the third hypothesis�此�plementary diploids from the same parents。 What would this experimenter do�拭�What would I do��
  
  I would use as near perfect stock as I could find and not start the experiment until I had both a male and a female parent who tested ;clean; geically in the most subtle ways for which I could test´which on Blessed meant quite sophisticated ways�察�for that century。 For a selected gene site and an assumption of 50´50 in the Mendelian distribution of 25´50´25�察�this pre´experiment testing would chop off the 25 percent chance of reinforcement of a bad recessive and leave a distribution of one´third bad�察�two´thirds good�察�at the parent generation´possible parents of possible Joes and Llitas�察�that is。
  
  Now I start putting together mirror twins in my persona as a 'priest´experimenter。 What happens�拭�If we consider the minimum number of gametes needed to represent this ohird and two´thirds distribution�察�we get eighteen possible ;Joes�察─�eighteen possible ;Llitas;´but in both male and female two of them show up as ;bad;´the bad recessive has reinforced and the zygote is defective�察�the experimenter eliminates them 。 。 or he may not need to�察�the reinforcement may be lethal。
  
  We wind up at this point with an 8 & 1/3 percent improvement�察�or a total improvement of 25 percent in favorable chances for Llita's baby。 I felt better。 If you add the fact that I am the sort of a midwife who is too busy helping the mother to stop to spank a monster�察�the favorable chances went way up。
  
  But all that this shows is that bad genes tend to be eliminated at each generation´with the tendency greatest with the worst genes and reaching 100 percent whenever reinforcement produces a lethal´in´womb´while favorable genes are conserved。 But we knew that´and it applies also to normal outbreeding and even more strongly to inbreeding�察�although the latter is not well thought of for humans as it hikes up the chances of a defective by precisely the same amount that it weeds´that being the hazard that I was afraid of for Llita。 Everybody wants the human gene pool cleaned up�察�but nobody wants its tragic aspects to take place in his own family。 Minerva�察�I I was beginning to think of these kids as ;my family。;
  
  I still did not know anything about ;mirror twins。; I decided to investigate a more probable incidence of bad recessives at a given site。 Fifty´fifty is far too high for a really bad gene�察�the weeding is drastic�察�and the incidence drops to a lower percentage each generation�察�until the incidence of a particular bad gene is so low that reinforcement at fertilization is a rare event�察�as reinforcement is the square of the incidence�察�e。g。�察�if one´in´a´hundred haploids carry this bad gene�察�then it will be reinforced one´in´ten´thousand fertilizations。 I speak of the total gene pool�察�or in this case a minimum of two hundred adult zygotes�察�female and male�察�random breeding in such a pool will bring together that bad reinforcement only by that long chance´a chance happy or unhappy depending on whether you look at it impersonally in terms of cleaning the gene pool or personally in terms of individual human tragedy。
  
  I looked at it very personally�察�I wanted Llita to have a healthy baby。
  
  Minerva。 I'm sure you recognized that 25´50´25 distribution as representing the most drastic case of inbreeding�察�one which can happen only half the time with line breeding�察�only a quarter of the time with full siblings�察�in both cases through chromosome reduction at meiosis。 A stockbreeder uses this drastic measure regularly´and culls the defectives and winds up with a healthy stabilized line。 I have a nasty suspicion that such culling after inbreeding was sometimes used among royalty back on old Earth´but certainly such culling was not used often enough or drastically enough。 Royalism might work quite well if kings and queens were treated like racehorses´but regrettably they never were。 Instead�察�they we��e propped up like welfare clients�察�and princelings who should have been culled were encouraged to breed like rabbits´bleeders�察�feebleminded�察�you name it。 When I was a kid�察 �royalty;
  
  was a bad joke based on the worst possible breeding methods。
  
  Captain Sheffield investigated next a lower incidence of a bad gene�此�Assume a lethal gene in the gene pool from whi h Joe and Llita's parents。 were derived。 Being lethal�察�it。 could exist in an adult zygote only if it was masked in gene´pair by its benign twin。 Assume a 5 percent masked incidence in zygotes´still too high to be realistic for a lethal gene´but check it anyhow。 What trend would show��
  
  Parent zygote generation�此�100 females�察�100 males�察�each a possible parent for Llita and for Joe´and 5 of the females and 5 of the males carry the lethal gene�察�masked。
  
  Parent haploid stage�此�200 ova�察�5 of which carry the lethal gene�察�200 spermatozoa�察�5 of which carry the lethal gene。
  
  Son´and´daughter zygote generation ��possible ;Joes; and possible ;Uitas;���此�25 dead through reinforcement of lethal gene�察�1��950 carrying the lethal gene masked�察�38��025 ;clean; at that site。
  
  Sheffield noted that a hypothetical hermaphrodite had crept in through not doubling his sample size in order to avoid anomaly through odd numbers�察�Oh�察�the hell with� �it did not change the statistical oute。 No�察�do it� �start with a sample of 200 males and 200 females with the same lethal´gene incidence for that site。 This gave him��
  
  400 ova�察�10 with the lethal gene��
  
  400 spermatozoa�察�10 with that lethal gene´10'��
  
  ´which gave in the next zygote generation ��possible ;Joes; and ;Llitas;���此�100 dead�察�7��800 carriers�察�152��100 ;clean;´ which changed no percentages but got rid of that imaginary hermaphrodite。 Sheffield considered briefly the love life of an hermaphrodite�察�then got back to work。 The numbers became very cumbersome�察�jumping to the billions in the next zygote generation ��i。e。�察�Little Nameless�察�now just started in Llita's belly ��´l 5��210��000 culled by reinforcement�察�1。216。800��000 carriers�察�24��336��000��000 ;clean;´and again he wished for a clinic puter and tediously converted the unhandy numbers into percentages�此�0。059509 percent�察�4。759 percent�察�95。18 percent plus。
  
  This showed a decided improvement�此�approximately 1 defect out of 1��680 ��instead of 1 out of 1��600���察�the percentage of carriers decrease to below 5 percent and the number of ;clean; increased to above 95 percent in one generation。
  
  Sheffield worked several such problems to confirm what he had seen by inspection�此�A child from plementary diploid �─�mirror twins;�� had at least as much chance of being healthy as did the offspring of unrelated strangers´plus the happy fact that such a baby's chances were improved by culling at one or more stages by the priest´scientist who had initiated the experimention ´ almost certain assumption and one that made Joe the best possible mate for his ;sister; rather than the worst。
  
  Llita could have her baby。
  
  VARIATIONS ON A THEME
  
  VII
  
  Valhalla to Landfall
  
  ´the best I could for them�察�Minerva。 Every so often some idiot tries to abolish marriage。 Such attempts work as well as repealing the law of gravity�察�making pi equal to three point zero�察�or moving mountains by prayer。 Marriage is not something thought up by priests and inflicted on mankind�察�marriage is as much a part of mankind's evolutionary equipment as his eyes�察�and as useful to the race as eyes are to an individual。
  
  Surely�察�marriage is an economic contract to provide for children and to take care of mothers while they bear kids and bring them up´but it is much more than that。 it is the means this animal�察�Homo sap。�察�has evolved´quite unconsciously´for performing this indispensable function´and be happy while doing so。
  
  Why do bees split up into queens�察�drones�察�and workers�察�then live as one big family�拭�Because�察�for them�察�it works。 How is it that fish do okay with hardly a nodding acquaintance between mama fish and papa fish�拭�Because the blind forces of evolution made that way work for them。 Why is it that ;marriage;´by whatever name´is a��universal institution among human beings everywhere�拭�Don't ask a theologian�察�don't ask a lawyer�察�this institution existed long before it was codified by church or state。 It works�察�that's all�察�for all its faults it works far better by the only universal test´survival´than any of the endless inventions that shallow´pates over the millennia have tried to substitute for it。
  
  I am not speaking monogamy�察�I mean all forms of marriage´monogamy�察�polyandry�察�polygyny�察�plural and extended marriages with various thrills。 ;Marriage; has endless customs�察�rules�察�arrangements。 But it is ;marriage; if´and´only´if the arrangement both provides for children and pensates the adults。 For human beings�察�the only acceptable pensation for the drawbacks of marriage lies in what men and women can give each other。
  
  I don't meast ;Eros��~' Minerva。 Sex baits the trap�察�but sex is not marriage�察�nor is it reason enough to stay married。 Why bteed a cow when milk is cheap��
  
  panionship�察�partnership�察�mutual reassurance�察�someone to laugh with and grieve with�察�loyalty that accepts foibles�察�someone to touch�察�someone to hold your hand´

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